Scientists from Germany offered against infections cure new principle of action.
Scientists from the universities of Stuttgart and tübingen (Germany) found that Orchid species Clusia rosea contain potential antibiotics polycyclic polyprionidae of azithromgcin (PPAP), which will help in the fight against multiresistant bacteria. These substances correspond in their activity popular backup antibiotics (vancomycin, – teicoplanin), but at the same time do not violate the biosynthesis of the cell wall. Simple chemical transformations PPAP will produce inexpensive medicines in industrial scale. Details about the study reported in the journal Angewandte Chemie.
Applied reserve antibiotics based on complex peptides that block the biosynthesis of the cell wall. However, increasingly there are news of new resistant strains, e.g. of Staphylococcus aureus to vancomycin. Scientists believe that these bacteria can handle PPAP, showed efficacy against seven strains of distressed and low toxicity against human cells.