New effective means for the treatment of hepatitis C can be a substance extracted from rattlesnake venom, this data was obtained by Brazilian scientists from the University of Sao Paulo. Also the drug based on snake venom could help in the fight against other dangerous viruses.
The authors of the study analyzed the effect of two protein substances, isolated from the venom of rattlesnake Crotalus durissus terrificus,– those were phospholipase A2 (PLA2-CB) and katapatan. These substances were tested separately and in combination.
The results of laboratory experiments with infected cells were as follows. Phospholipase A2 showed the ability to prevent reproduction of hepatitis C virus by approximately 86%. Efficiency crotoxin was not as high but still significant – 58%.
At the same time it became clear that dedicated scientists proteins give a powerful preventive effect, blocking the invasion of the virus into cells. In clinical trials on healthy human cells phospholipase helped prevent the onset of the disease in 97% of cases, crotoxin – in 85% of cases.
“Snake venom showed high efficacy against some viruses, including measles and dengue fever; the latter belongs to the same family as the hepatitis b virus,” noted the scientists.
Hepatitis C – an inflammatory disease of the liver. The main route of HIV through dirty needle infection by the penetration of the virus through the mucous membranes during unprotected sexual contact. Hepatitis C virus has a distinctive perfidy: it is easy to deceive the human immune system, regularly modificeres.
Liver damage hepatitis C is accompanied by a concomitant internal diseases, various metabolic disorders, and immune system. While existing drugs for hepatitis C are very expensive and difficult tolerated by the patients.