Evaluated the efficacy of omega-3 PUFA in reducing the symptoms of dry eye syndrome

The use of omega-3 polyunsaturated fatty acids (PUFA) does not ease the symptoms of dry eye syndrome, results of a study published in the New England journal of Medicine.

As you know, dry eye syndrome is a common chronic disease characterized by discomfort in the eyes or vision disorders which reduce the patient’s quality of life. For the relief of symptoms, many clinicians recommend the use of supplements of omega-3 PUFA.

In the framework of a multicenter double masked study of patients with moderate or severe dry eye syndrome were randomized into groups, one of which (329 people) daily was orally administered 3000 mg of omega-3 Pufas eicosapentaenoic acid and docosahexaenoic acid, the second (170), olive oil (placebo-group).

Each participant took 5 capsules per day. One capsule in the experimental group contained 400 mg eicosapentaenoic acid and 200 mg docosahexaenoic acid, and each capsule in placebo group and 68% oleic acid, 13% palmitic acid, 11% linoleic acid. All capsules also contain vitamin E.

Symptoms and signs of dry eye were improved to the same extent in patients treated with supplements of omega-3 PUFA for 12 months, and that participants in the placebo group. “Significant differences between the two groups in the improvement of the four key symptoms of dry eyes were found,” concluded the authors.

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