Correlation between prolonged use of aspirin and the risk of developing melanoma

Men who take aspirin daily for more than one year, are at increased risk of developing malignant melanoma, according to a study published in the journal of the American Academy of Dermatology.

The study analyzed data on patients from Chicago who took aspirin (81 or 325 mg) every day for at least one year continuously. The observation period was five years. The control group consisted of patients not taking the drug daily. In General, the study used data from more than 193 thousand patients.

Managed to establish that, in General, the relative risk of developing malignant melanoma after a long use of aspirin was $ 1.46 compared to the control group. However, after stratification of patients according to gender the relative risk of spillage of malignant diseases in men who took aspirin made up 1.83. Among women, these relationships have been identified.

“Given the widespread use of aspirin and the potential clinical impact on communication with melanoma patients and medical professionals should be aware of the likelihood of increased risk in men, noted the authors. – However, the results do not mean that men who take aspirin for cardioprotection should stop therapy”.

Without naming the mechanism of action to explain the results, scientists suggest that the identified relationship may be correlated with hormonal differences between men and women.

Источник